|
TERM
|
DEFINITION
|
|
Ablation
|
Detachment or removal, as of an organ or part, especially by surgery. Also,
destruction of function, as by a chemical.
|
|
Aminoglycoside
|
A class of antibiotic drugs often used for selective ablation of the vestibular
endorgan. Examples are streptomycin and gentamicin; both have
their main toxic effects on vestibular hair cells and dark cells,
and to a lesser extent, on cochlear hair cells.
|
|
Ampulla
|
The dilated or expanded end of each of the three membranous semicircular
ducts of the inner ear.
|
|
Ataxia
|
Impaired coordination, especially in gait.
|
|
Audiometric assessment
(AA)
|
Overall assessment of hearing function. Includes the threshold of hearing at
different frequencies of the hearing spectrum, both by air conduction and bone
conduction, which thereby analyzes the contribution of the middle vs. inner ear
structures. Also, includes tests of the ability to discriminate speech.
|
|
Auditory
|
Refers to the sense of hearing.
|
|
Auditory brainstem response audiometry (ABR)
|
Method for computer analysis of retrocochlear (neural pathways between the
cochlea and the brain) function by means of electrodes placed on the head and
ears. Specifically, to detect and localize a lesion affecting the auditory portion
of the eighth nerve or its higher pathways.
|
|
Automated positioning
|
Use of an automated apparatus to position the patient. Used for analysis of
positional nystagmus and for treatment of various forms of vestibular lithiasis.
|
|
Automated repositioning
|
Treatment of canalithiasis (BPPV) or cupulolithiasis by repositioning
of abnormal labyrinthine densities with an automated positioning apparatus. Ideally
this is accomplished with equipment that has a 360-degree range in any axis and
an IR video system to monitor and record nystagmus during the procedure. This
is the most effective method for treating difficult cases of BPPV and variants.
|
|
Benign paroxysmal positional vertigo (BPPV)
|
A condition in which violent, brief (seconds) episodes of spinning vertigo
are provoked by moving the head into certain positions. The mechanism is abnormal
densities, mainly displaced otoconia from the utricle, which collect in
a posterior semicircular canal, where they shift position when the head
is tilted. The diagnosis is made by observing typical nystagmus after the
Hallpike maneuver. Treatment: the offending loose densities can be moved
out of the semicircular canal with the Epley (canalith repositioning)
maneuvers, thus controlling the symptoms.
|
|
BPPV variant
|
Vertigo due to any other form of vestibular lithiasis besides typical
posterior canal canalithiasis.
|
|
Biphasic nystagmus
|
Involuntary eye movement occurring with a fast phase in one direction and a
slow phase in the opposite direction. Also called "jerk nystagmus".
It is generated in the vestibular system. By convention, the nystagmus is designated
by the direction of its fast phase.
|
|
Brainstem
|
Composed of the pons, the medulla oblongata, and the nuclei of the cranial
nerves. It receives information relating to balance and initiates muscle adjustments
that enable one to keep their balance and to maintain clear vision as they move.
|
|
Caloric test
|
Method for assessing the relative function of the horizontal semicircular canals
by means of warm or cool stimulus presented to external ear canals. Does not assess
function of the otolith organs (utricle and saccule).
|
|
Canalith
|
Free-floating density in a semicircular canal. Can be displaced otoconia,
calcified masses or layering of endolymph.
|
|
Canalithiasis
|
A condition in which loose densities in a semicircular canal produce nystagmus
and vertigo when a critical provocative position of the head is assumed. The symptoms
generated are called benign paroxysmal positional vertigo (BPPV).
|
|
Canalith Repositioning
|
Procedure for the treatment of canalithiasis (BPPV) through maneuvers designed
to induce migration of free particles out of the semicircular canals, assisted
by concurrent observation of the nystagmus being produced by the migrating particles.
Also known as the "Epley Maneuvers".
|
|
Central compensation
|
The tendency of the central nervous system to respond to impaired function
or defect by a change in its activity that counterbalances the impairment or defect.
|
|
Central nervous system (CNS)
|
The part of the nervous system that integrates sensory input and motor output;
made up of the brain and spinal cord.
|
|
Cerebellum
|
Muscle coordination center of the brain.
|
|
Cerebrum
|
The main part or mass of the brain. Consists of two equal portions, known as
hemispheres.
|
|
Cervical vertigo syndrome (Post-traumatic)
|
A theoretical condition unsupported by any study. There is no reliable clinical
test for the syndrome, no typical time course for the condition has been established,
and treatment directed at the neck has not proven to be generally effective. (The
symptom complex is identical to the "inner ear concussion syndrome."
Most cases assigned the diagnosis of "cervical vertigo" actually have
the sequella of inner ear concussion.)
|
|
"Chronic disabling vertigo"
|
A term used by a small group of physicians to describe a condition supposedly
resulting from vascular compression of the eighth nerve. Treatment by intracranial
vascular decompression was advocated. In the few published cases pegged with CDV
and surgerized, the symptoms have been strikingly similar to those of severe canalithiasis
(BPPV); further, they were not given a preliminary trial of canalith repositioning.
Therefore, it is likely that most cases, if not all, actually had canalithiasis.
|
|
Cochlea
|
The snail-shaped portion of the inner ear which is concerned with hearing.
|
|
Cochlear duct
|
A canal, triangular in cross section, situated in the cochlea between
the scala tympani (lower canal of the cochlea) and scala vestibuli (upper
canal of the cochlea). It is filled with a fluid called endolymph,
and it contains the organ of Corti, the ultimate mechanism that transforms sound
into nerve impulses that are transmitted to the brain by the cochlear nerve
for interpretation.
|
|
Cochlear nerve
|
One of the two components of the acoustic (eighth) nerve. The other
part is the vestibular nerve. The cochlear nerve is concerned with
hearing.
|
|
Computerized dynamic posturography
(CDP)
|
A test that obtains a computer analysis of the overall balance function, and
identifies those sensory or motor systems that are contributing to imbalance because
of a deficit or improper utilization. The test subject stands on a moveable force
platform that has a moveable visual background.
|
|
Concussion
|
A sudden and violent jarring or shaking (result of high g-forces), resulting
in injury to soft tissue, specifically in the CNS or inner ear. Does not necessarily
require a direct traumatic blow.
|
|
Corticosteroid
|
A steroidal anti-inflammatory drug. Dexamethasone is an example.
|
|
Cupula, cupulae
|
A fine striated membranous structure covering the hair cells of the crista
of the ampulla of each semicircular canal. The cupulae are
deflected by inertial movement of fluid in the semicircular canal, whereby
the canals are mechano-receptors of angular acceleration in the specific
plane of the canal.
|
|
Cupulolithiasis
(Heavy cupula)
|
A condition created when a cupula is weighted by densities. The nystagmus produced
is slow in onset and persistent.
|
|
Dark cells
|
Pigmented cells in the inner ear that secrete endolymph.
|
|
Eighth nerve
|
Nerve that carries impulses concerned with balance and hearing between the
inner ear and the brain.
|
|
Electrocochleog-raphy
(ECoG)
|
A test to analyze the overall cochlear function and the relationship between
the cochlear fluids, especially to identify endolymphatic hydrops. Uses
sound stimuli and electrical potentials detected via an electrode in the EAC
to do a computer analysis of the cochlear response.
|
|
Electronystagmog-raphy
(ENG)
|
Battery of tests using electrodes placed around the eye to monitor eye movement.
Assesses the vestibulo-ocular reflex portion of the vestibular system,
including the oculomotor function through introduction of various stimuli. Typical
battery includes caloric, gaze, positional and oculomotor stimuli. Will
also assess the ability of the CNS to suppress nystagmus during optic fixation.
Does not assess function of the otolith organs (utricle and saccule).
|
|
Endolymph
|
The fluid contained within the membranous labyrinth.
|
| Endolympatic
fluid |
Fluid contained within
the inner compartment of the inner ear. |
|
Endolymphatic duct
|
A duct which arises from the saccule and utricle and ends in
the endolymphatic sac. Believed by some to have an important role in the
production of endolymphatic hydrops.
|
|
Endolymphatic sac
|
The dilated blind end of the endolymphatic duct.
|
|
Endolymphatic hydrops (EH)
|
Abnormal accumulation of endolymph fluid which results in a dilatation
of the membranous labyrinth. It can cause the symptoms of Meniere’s
disease.
|
|
Endolymphatic shunt procedure
|
Surgery to permanently drain the endolymphatic sac via a shunt tube either
into the middle ear space or the subarachnoid space.
|
|
Epley Maneuvers
|
A procedure for correcting the symptoms of BPPV (canalithiasis) through
maneuvers designed to induce migration of free particles out of the semicircular
canals, assisted by concurrent observation of induced nystagmus. Also known as
"canalith repositioning" or, when used more broadly to treat the various
manifestations of vestibular lithiasis, the treatment is called
"particle repositioning".
|
|
External auditory canal (EAC)
|
Ear canal external to the tympanic membrane.
|
| External
ear canal |
Outer opening of the
ear. |
|
Fistula
|
An abnormally formed canal or passage running between two organs or spaces
within the body, or between the surface of the body and an internal organ or a
space inside the body.
|
|
"Fistula test"
|
This term originally described a test involving the application of positive
and/or negative pressure to an EAC for detecting a softening in a bony erosion
(softening) of a semicircular canal as indicated by a severe induced nystagmus.
In the 1970’s, the term "fistula test" began to be misused to denote
the Hennebert test, thus incorrectly inferring that the test is diagnostic
of a perilymph fistula.
|
| Gentamicin |
Antiobiotic that is
selectively toxic to the vestibular endorgan. |
|
Glycerol test
|
A test that indicates the presence of endolymphatic hydrops (EH).
Ingestion of glycerol solution causes rapid absorption of fluid from endolymphatic
system. A positive test is indicated by ± 10 db change in hearing at any frequency
or a 12% improvement in speech discrimination.
|
| Habituation |
The process of developing
tolerance to a factor through repeated exposure. |
|
Hallpike test, Hallpike maneuver
|
A physical maneuver that rotates the posterior semicircular canal in the plane
of gravity during which the eyes are observed for a characteristic pattern of
movement (typical nystagmus) diagnostic of BPPV. From a sitting position,
the patient is moved quickly to a supine position with the head over the end of
the table and turned 45 degrees to the side of the ear being tested.
|
|
Hennebert phenomenon
|
The production of induced eye movement, vegetative symptoms (nausea, vomiting,
paleness, etc.) and postural instability in response to air pressure applied to
an external auditory canal with an intact tympanic membrane.
|
|
Hennebert sign
|
Observation of induced eye movement in response to air pressure applied to
an external auditory canal with an intact tympanic membrane. The
induction of biphasic nystagmus is consistent with a bony defect in the
semicircular canal in the plane of the nystagmus. Induction of static torsion
of the eyeball proportional to the pressure applied (positive or negative) is
consistent with otolithic membrane involvement, most likely by vestibular
fibrosis.
|
|
Hennebert symptom
|
Subjective sensation of motion, nausea or imbalance in response to air pressure
applied to an external auditory canal with an intact tympanic membrane.
|
|
Hennebert test
("pressure test")
|
Application of air pressure, positive and/or negative, to an external auditory
canal (EAC) with an intact tympanic membrane, usually with the patient
seated. Simultaneously the eyes are observed for nystagmus and the patient
reports any sensation of movement, nausea, imbalance, etc. Any positive sign or
symptom is abnormal, but the interpretation of the abnormality depends upon the
characteristics of that sign or symptom. (See Hennebert sign, Hennebert symptom)
NOTE: This test is also frequently called a "fistula test" in relation
to a perilymph fistula. This is a misinterpretation because, although a
positive sign or symptom is suggestive of the presence of a perilymph fistula,
it is not diagnostic of one. Thus, the use of the term "fistula
test" is confusing, and should be avoided.
|
|
Hydrops
|
An abnormal accumulation of fluid in an organ, a body cavity, or in a tissue.
|
|
Hyperactive labyrinthine dysfunction
|
The condition in which a labyrinth is in an abnormally sensitive state
with respect to certain stimuli and/or inputs. More appropriately called "irritable
labyrinth", in that the labyrinth becomes easily "irritated"
by non-vestibular stimuli such as sound or pressure change.
|
|
Infrared video-graphy
(IR Videonystag-mography)
|
Use of video camera in apparent darkness (with infrared light) to record eye
movement for recording and analysis. This test method is far superior to eye electrode
ENG, because it is more sensitive, less affected by artifact, and because
it provides assessment of any torsional component of eye movement, which
is of great importance in identifying the source of some types of vertigo.
|
|
Inner ear (Labyrinth)
|
Consists of a complex cavitation in the temporal bone and is divisible into
three parts, the vestibule (in the middle), cochlea (in front),
and semicircular canals (in the back). All three parts form a continuous
and tortuous cavitation which is lined loosely by a membrane (membranous labyrinth)
separated from the bone surface by a fluid called perilymph. The membranous
labyrinth, like most linings of the body, is in substance a sac with intricate
ramifications. Its cavity contains a fluid called endolymph. The hearing
portion of the labyrinth is the cochlea. The balance portion consists
of the vestibular endorgans.
|
|
Inner ear concussion (IEC)
|
Indirect trauma and violent jarring of the membranous structures of the inner
ear.
|
|
Inner ear concussion syndrome (Labyrinthine concussion
syndrome)
|
A controversial syndrome consisting of chronic lightheadedness, imbalance,
nausea, cognitive dysfunction, etc. (The same symptoms have been called "post-concussive
syndrome," "perilymph fistula syndrome," "minor head trauma
syndrome," "cervical vertigo syndrome," "whiplash syndrome,"
etc.). The proof of inner ear origin has been through the excellent symptomatic
improvement noted with treatment of the ear.
|
|
Intratympanic (transtympanic) perfusion of the round
window
|
The delivery of medication into the middle ear (tympanic cavity) by way of
an opening in the tympanic membrane, whereupon it is perfused against the
round window membrane whence it diffuses into the inner ear.
The amount reaching the inner ear is proportional to the concentration of
the medication times the amount of time that concentration is in contact with
the membrane.
|
|
Intratympanic (transtympanic) perfusion of streptomycin.
(IPS)
|
Perfusion of streptomycin through the tympanic membrane into the middle
ear so as to obtain diffusion through the round window membrane into the inner
ear. The indications for IPS are:
(1) chronic, intractable, disabling vertigo; (2) symptoms generated
predominantly in labyrinth to be treated; (3) more conservative treatment
not appropriate (as determined by trial or prior experience); (4) adequate vestibular
and cochlear function in the contralateral ear; and (5) adequate compensatory
function of the CNS.
|
|
Intratympanic perfusion of gentamicin (IPG)
|
See "intratympanic (transtympanic) perfusion." Gentamicin
is an aminoglycoside antibiotic, with similar action and indications to streptomycin.
Used mainly for treatment of Meniere’s disease, but can be effective in ablating,
partially or completely, an aberrant labyrinth regardless of the pathophysiology
involved.
|
|
Intratympanic perfusion of corticosteroids (TPC)
|
See "intratympanic (transtympanic) perfusion." Corticosteroids
are anti-inflammatory medications. Indications for this use are not standardized,
but it has proven to be very effective against a variety of cochlear and labyrinthine
conditions.
|
|
Irritable (irritative) labyrinthine focus; "irritable
labyrinth"
|
Abnormal, erratic (unstable) function of a labyrinth that acts as a source
of vertigo or imbalance. This abnormality usually results from disease
or trauma affecting the vestibular mechano-receptors, causing them to become
abnormally receptive to non-vestibular stimuli, such as sound, pressure or gravitational
change. If this focus is constantly being irritated (stimulated), the erratic
input creates a constantly changing sensory mismatch of the patient’s vestibular
perception of spatial orientation compared to the accurate visual and somatosensory
cues. The brain may be unable to compensate for this persistent instability, leaving
the patient with chronic, disabling vertigo and/or imbalance.
|
|
Labyrinth
|
See inner ear.
|
|
Labyrinthectomy
|
Destruction of the labyrinth, or its function.
|
|
Labyrinthine anesthesia test(LAT)
(Temporary pharmacological labyrinthectomy)
|
Involves placing local anesthetic intratympanically into the suspect ear, and
allowing it to absorb through the round window into the inner ear. If this temporarily
resolves or ameliorates the ongoing vertiginous signs or symptoms, or the postural
instability, then the test ear can be assumed to be the major source of these
signs or symptoms. It can also detect residual labyrinthine function not detectable
by caloric testing.
|
|
Labyrinthine deficit
|
Decreased function of the labyrinthine sensors. With time, central compensation
will typically occur if the deficit remains stable.
|
|
Labyrinthine dysfunction
|
Abnormal, but not necessarily decreased, function of a portion of the labyrinthine
sensors. In proportion to which labyrinthine function is unstable and erratic,
the CNS is typically less effective in compensating for the abnormality.
|
|
Labyrinthitis
|
An inflammatory condition of the labyrinth.
|
|
Macula
|
A patch of hair cells in the saccule and utricle. The patch is
coated with a gelatinous layer that contains small granules called otoliths.
This provides sensory input of inertio-gravitational orientation.
|
| Malleus,
incus, stapes |
Hammer, anvil and stirrup
bones of the ear. |
|
Mechanoreceptors
|
Organic transducer made up of a mechanical portion that activates a neural
portion. It provides a specific function by reacting only to a certain form of
stimuli. Example 1: a semicircular canal, which consists of a curved,
fluid-filled tube with a flow sensor (cupula) at one end (mechanical) that
activates attached hair cells (neural). It reacts only to angular acceleration
(turning) in its plane. Example 2:
an otolith organ, which consists of heavy particles (mechanical) that
are attached to a bed of hair cells (neural). The direction of inertio-gravitational
pull on the heavy particles, and hence the hair cells, provides input as to head
position.
|
|
Membranous labyrinth
|
Membranous vessel comprising contiguous tubes and sacs contained within the
bony labyrinth. This contains endolymph and the sensory cells for hearing and
spatial orientation.
|
|
Meniere’s disease
|
A disease of the inner ear associated with dilatation of the membranous
labyrinth (endolymphatic hydrops) and characterized by
attacks of vertigo, fluctuating unilateral hearing loss and tinnitus.
The attacks last for minutes to hours.
|
|
Microcath®
|
A special, small, patented catheter designed to deliver intratympanic medications
to the inner ear, via the round window, over an extended period of time. The method
has the advantage of more accurate control of dose rate.
|
| Middle
ear cavity |
Air space behind the
tympanic membrane containing the ossicles. |
|
Morbidity
|
Illness; sickness; adverse symptoms and signs.
|
|
Motor coordination test (MCT)
|
A part of platform testing that assesses the reflexes of the muscles of postural
control in response to sudden movements of the platform. Detects abnormalities
of CNS function and of the motor pathways.
|
|
Nystagmus
|
Involuntary (reflex) alternating movements of the eyeballs, induced normally
by active or passive head motion; induced abnormally by disease conditions in
the labyrinth or CNS. Nystagmus may also be induced during certain tests (caloric,
Tullio, Hennebert, etc.). See biphasic nystagmus.
|
|
OMNIAX
|
Omniaxial automated chair that can place a patient in any position relative
to gravity, and move them through any plane. When combined with IR nystagmography,
it is a valuable tool for both the diagnosis and treatment of certain vestibular
disorders.
|
|
Ossicles
|
Malleus, incus, stapes. The three tiny bones of the middle ear that
conduct sound from the tympanic membrane to the oval window of the inner ear.
|
|
Otalgia
|
Pain in the ear; earache.
|
|
Otic capsule
|
Bone surrounding the inner ear.
|
|
Otolith, otoconia
|
Calcium carbonate crystals normally attached to a membrane in the otolith
organs (utricle and saccule) within the vestibule of
the inner ear. They provide inertio-gravitational sensation. These crystals
can break off from this membrane in the saccule for various reasons and migrate
into a semicircular canal, causing symptoms of BPPV.
|
|
Otolith organs
|
The utricle and saccule are the otolith organs. They lie
within the otic capsule on the medial wall of the vestibule. Each includes
a membranous sac containing fluid (endolymph). Within each sac is a macula,
a flat membrane that projects sensory hair cells to its overlying otolithic membrane.
The otolith organs are "mechanoreceptors," which are organic transducers
made up of a neural and a mechanical portion. They are normally responsive to
gravitation and other linear acceleration forces. If they become abnormally responsive
to sound and/or pressure (irritative focus); the result is vertigo
and/or imbalance.
|
| Otolithic
endorgan |
The sensory organ of
the ear that is receptive to inertia and gravity(both of which are expressions
of linear acceleration). |
| Otolithic
membrane |
Gelatinous membrane
in the utricle and saccule in which are imbedded the otoconia (otoliths). |
|
Ototoxic
|
Toxic to the sensory cells of the inner ear (cochlear and vestibular
endorgans).
|
|
Oval window
|
Oval-shaped opening into the inner ear. The footplate of the stapes
fits into the oval window.
|
|
Particle repositioning
|
Procedure for repositioning of symptom-causing particles in the semicircular
canals, whether initially free or attached to a cupula. so that they no longer
cause symptoms.
|
|
Perilymph
|
The fluid contained in the space surrounding the membranous labyrinth but within
the osseous (bony) labyrinth. This fluid is contiguous with the cerebro-spinal
fluid via small openings.
|
|
Perilymphatic fistula (PLF)
|
An abnormal opening (leak) between the labyrinth and the middle ear
space, commonly located at the outer margin of the stapes footplate. Thought to
be most often caused by trauma, but may also be congenital or a complication of
ear surgery. Significance and frequency are very controversial.
|
|
Positional nystagmus and vertigo
|
Nystagmus and vertigo that are precipitated or aggravated by
certain position changes or assumptions, usually in relation to gravity.
|
|
Post-traumatic vertigo
|
Vertigo which follows trauma. Most commonly occurs when an irritable
labyrinthine focus develops in the weeks to months following the incident.
Other causes of post-traumatic vertigo include vestibular lithiasis,
PLF, and endolymphatic hydrops (EH).
|
|
Post-treatment morbidity
|
The untoward symptoms and signs that result from a treatment procedure, as
from surgery, chemotherapy or transtympanic perfusion with aminoglycosides.
|
|
Postural Hennebert test
|
Also known as the "platform pressure test", or "pressure
evoked (postural) destabilization (PED) test". It is the application
of air pressure to an EAC with the patient standing. It tests for postural
destabilization, which is an abnormal response to pressure change of the vestibular
endorgans (otolith organs or semicircular canals). When performed on
a force platform, which quantifies and documents the postural stabilization, it
is often called the "platform pressure test". It has also been called
a "platform fistula test", which is a misnomer because this, and the
various other pressure tests, are suggestive of, but not diagnostic of,
a perilymphatic fistula.
|
|
Postural Tullio test
|
Also known as the sound evoked (postural) destabilization (SED)
test. It is the presentation of sound to the test ear with the patient standing
and observed for increased postural destabilization as well as other factors.
It serves to detect and localize abnormal vestibular endorgans)
and determines their threshold of receptivity to sound stimuli. Most commonly,
a 500-Hz pure tone is presented in ascending fashion until a threshold of destabilization
is noted. A force platform may be used in assessment.
|
|
Posturography
|
Analysis of postural responses with a force platform.
|
| Pressure
evoked (postural) destabilization (PED) test |
A test whereby air
pressure is applied to the external auditory canal with the patient standing freely.
It is positive if the patient loses stability. It is usually indicative of hyperactive
labyrinthine dysfunction originating in an otolith organ. |
|
Pressure test
|
See Hennebert test
|
|
Pre-treatment morbidity
|
State of the illness, and level of symptoms, present immediately before the
institution of treatment.
|
|
Psychotropic
|
Denotes substance that affects psychic function or behavior.
|
|
Romberg sign
(Romberg test)
|
A sign manifested by unsteadiness or loss of position sense when the patient
is asked to stand with feet close together and eyes closed. If the patient sways
severely or falls, the sign (test) is positive.
|
|
Round window
|
Membrane separating the middle ear space and the fluid of the inner ear. It
lies deep in the round window niche.
|
|
Saccule
|
A sac located in the vestibule that contains an otolith organ.
It is a part of the membranous labyrinth of the inner ear.
|
|
Semicircular canals
|
Circular bony tube extensions of the labyrinth, with three on each side
lying in orthogonal planes. Each contains a fluid duct (containing endolymph)
with a dilated end (ampulla) containing a sensor (cupula) of fluid
motion. By virtue of the endolymph being forced by inertia against the
cupula during head movements, the semicircular canals act as mechanoreceptors
(sensors) of angular acceleration (turning) in the plane of the canal.
|
|
Semicircular ducts
|
The membranous ducts lying within the osseous (bony) semicircular canals, and
containing endolymph.
|
|
Sensorineural hearing loss (SNHL)
|
"Nerve loss" involving the cochlea or its central pathways.
|
|
Sensory conflict (mismatch)
|
A condition experienced in which the perceptions obtained through the senses
of spatial orientation (visual, vestibular and somatosensory) do not match. This
typically creates nausea.
|
|
Sensory organization test (SOT)
|
A test designed to assess the relative contribution of visual, vestibular of
somatosensory sensory input to postural stability (or instability). Determined
through the relative stability under 6 different test conditions on a force platform.
|
| Sound
evoked (postural) destabilization (SED) |
A test whereby sound
is presented to the ear via an earphone headset with the patient standing freely.
It is positive if the patient loses stability, and can be quantified by noting
the intensity of the sound required to produce the positive effect. It is usually
indicative of hyperactive labyrinthine dysfunction originating in an otolith organ. |
|
SOT composite score
|
An arbitrary, single number assessment of overall postural stability based
on the average of 6 posturography test conditions.
|
|
Stenger test
|
A standard test for malingering of a unilateral sensorineural hearing loss.
|
| Streptomycin |
Antiobiotic that is
selectively toxic to the vestibular endorgan. |
|
Titration
|
Method of dosing medication whereby it is given only until a certain end point
effect is obtained. This end point may be the advent of the desired therapeutic
effect, or the onset of certain side effects.
|
|
Transtympanic
|
Through the tympanic membrane. See intratympanic.
|
|
Tullio phenomenon
|
The production of induced eye movement, vegetative symptoms (nausea, vomiting,
paleness, etc.), and/or postural instability in response to loud sound presented
to an ear.
|
|
Tullio test (standard)
|
A sound evoked test, in which the patient is observed for abnormal eye movement
phenomena during presentation of loud sound to one ear. The standard test, usually
performed with the subject seated, largely detects an abnormality of a semicircular
canal. It is much less useful than the postural Tullio test, performed
with the subject standing and observed for postural destabilization, which
detects otolithic organ dysfunction as well.
|
|
Tympanic membrane
|
The "eardrum," a thin, taut membrane that separates the external
ear canal from the middle ear air cavity.
|
|
Tympanovestibular coupling
|
A direct or indirect coupling between the tympanic structures (tympanic
membrane, ossicles, middle ear cavity) and a vestibular endorgan, with
the result that the vestibular endorgan is abnormally responsive to pressure
changes or sound vibrations transmitted from the tympanic structures.
|
|
Typical nystagmus (of BPPV)
|
The nystagmus seen in certain positions (i.e. Hallpike position) that
is pathognomonic for canalithiasis (BPPV). Essential elements are latency, quick
torsional movements toward the downward placed ear, torsional axis offset toward
downward ear and limited duration. Confirming elements are reversal of direction
after the precipitating movement is reversed, and decay in the response upon repetition
of the precipitating movement.
|
|
Utricle
|
A small sac in the vestibule of the inner ear that contains an
otolithic endorgan. It senses mainly tilt along the roll and pitch axes.
|
|
Vertigo
|
An illusion of movement. The illusion can be a sensation of rotation, linear
movement or tilt. Vertigo is frequently accompanied by symptoms of "imbalance"
and/or "nausea." Vertigo is usually due to a recent insult to
the balance system, usually occurring in the inner ear. It can also be
caused by abnormalities of the CNS. Most true vertigo originates in the
inner ear. Most vertigo is caused by one of the following four common dizziness
syndromes involving malfunction of the inner ear: (1) vestibular lithiasis,
including BPPV; (2) Meniere’s disease (endolymphatic hydrops);
(3) inner ear concussion; and (4) vestibular neuronitis ("acute
labyrinthitis").
|
|
Vestibular
|
Relating to the portion of the inner ear, and its central neural pathways,
involved in the sense of spatial orientation.
|
|
Vestibule
|
The vestibule of the ear is the central part of the inner ear cavity,
between the cochlea and semicircular canals. The utricle and
the saccule are within the vestibule, and the oval and round
window lead into it.
|
|
Vestibular endorgans
|
Utricle, saccule, and semicircular canals.
|
|
Vestibular hyperacusis
|
Abnormal sensitivity to noise in which the discomfort experienced is vestibular
in character (vertigo, imbalance, nausea). The mechanism is thought to involve
altered specificity of certain vestibular endorgans whereby they are abnormally
receptive to pressure change and sound.
|
|
Vestibular lithiasis
|
Any condition in which abnormal densities in the vestibular endorgan produce
nystagmus and/or vertigo. Includes both canalithiasis and cupulolithiasis,
and can involve any semicircular canal.
|
|
Vestibular mechanoreceptors
|
The semicircular canals and the otolith organs, (utricle
and saccule) are "mechanoreceptors," which are organic
transducers that respond to specific physical factors, in this case angular acceleration
or linear acceleration respectively. If they become abnormally sensitive (irritable
labyrinthine focus), then vertigo, imbalance or nausea are easily produced
by pressure change and/or sound.
|
|
Vestibular nerve
|
One of the two components of the eighth nerve. Serves the vestibular endorgans.
It is concerned with controlling equilibrium and stabilizing the eyes in space.
|
|
Vestibular nerve section
|
Surgical transection of the vestibular branch of the eighth (acoustic)
nerve. This is designed to completely and permanently eliminate all vestibular
input from that side. It is a major intracranial procedure with risks of CSF leak,
meningitis, facial nerve paralysis, unilateral hearing loss, etc. Rarely fatal.
|
|
Vestibular Neuronitis
|
An inflammation of viral origin involving a vestibular nerve that may cause
severe vertigo of days to weeks duration.
|
|
Vestibular rehabilitation therapy
|
Physical therapy methods designed to enhance central compensation as
well as habituation to non-physiologic changes in peripheral vestibular
input. Effective only when the peripheral lesion is essentially stable.
|
|
Vestibulo-ocular reflex (VOR) system
|
The portion of the vestibular system that uses rotational (angular)
sensory input from the semicircular canals to stabilize the eyes in space
through involuntary eye movements (nystagmus).
|
|
Vestibulopathy
|
Pathology of the vestibular system.
|
|
Vestibulo-spinal reflex (VSR) system
|
The portion of the vestibular system that uses inertio-gravitational
sensory input from the otolith organs to maintain balance by controlling
the muscles of postural control.
|